PRDM1 Mouse Monoclonal Antibody [Clone ID: ROS195G]
Specifications
| Product Data | |
| Clone Name | ROS195G |
|---|---|
| Application | WB |
| Recommended Dilution | WB, IHC, IP, IF, ELISA |
| Reactivity | Human, Mouse |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Recombinant GST-blimp-1 protein |
| Buffer | Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide. |
| Concentration | lot specific |
| Purification | The antibody was purified by affinity chromatography. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 98 Kd |
| Gene Name | PR domain 1 |
| Database Link | |
| Background | Blimp-1 is a 98 Kd protein containing five Kuppel-type zinc finger domains that confer sequence specific DNA binding. It has been postulated to be a master regulator of terminal B cell differentiation. In the BCL-1 lymphoma model of differentiation from mature B cells to plasma cells, ectopic expression of Blimp-1 is sufficient to cause terminal differentiation manifested by loss of surface immunoglobulin, IgM secretion, expression of syndecan-1 and cessation of cell division. Recently, it is reported that Blimp-1 is also involved in T cell differentiation and T cell homeostasis and suppression of IL-2 production. |
| Synonyms | BLIMP1; PRDI-BF1 |
| Reference Data | |
| Protein Categories | Cancer: Haematopoietic and Lymphoid, Intracellular Proteins, Transciption Factors |
| Protein Families | Transcription Factors |
Reviews
Documents
| Product Manuals |
| FAQs |
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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