CD1 (CD1A) Mouse Monoclonal Antibody [Clone ID: MTB1]
Specifications
| Product Data | |
| Clone Name | MTB1 |
|---|---|
| Application | IHC |
| Recommended Dilution | IHC: 1:10 - 1:50 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1, kappa |
| Clonality | Monoclonal |
| Buffer | This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | CD1a molecule |
| Database Link | |
| Synonyms | CD1; FCB6; HTA1; R4; T6 |
| Note | CD1a is a non-polymorphic major histocompatibitity complex class I-related cell surface glycoprotein (45 to 55 kDa) and is expressed in association with β-microglobulin. In normal tissues, anti-CD1a reacts with cortical thymocytes, Langerhans cells, interdigitating dendritic cells, and rare antigen-presenting cells of the lymph node.Anti-CD1a labels Langerhans cell histiocytosis (Histiocytosis X), extranodal histiocytic sarcoma, a subset of T-lymphoblastic lymphoma/leukemia, and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibodies against TTF-1 and CD5, anti-CD1a is useful in distinguishing between pulmonary and thymic neoplasms since CD1a is consistently expressed in thymic lymphocytes in both typical and atypical thymomas, but only focally in 1/6 of thymic carcinomas and not in lymphocytes in pulmonary neoplasms. Anti-CD1a was reported to be a new marker for perivascular epithelial cell tumor (PEComa). |
| Reference Data | |
| Protein Categories | CD Markers, Membrane Proteins |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Hematopoietic cell lineage |
Reviews
Documents
| Product Manuals |
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Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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