Cd19 Mouse Monoclonal Antibody [Clone ID: MRQ-36]
Specifications
| Product Data | |
| Clone Name | MRQ-36 |
|---|---|
| Application | IHC |
| Recommended Dilution | IHC: 1:25 - 1:100 |
| Reactivity | Human |
| Antibody Host | Mouse |
| Isotype | IgG1, kappa |
| Clonality | Monoclonal |
| Buffer | This antibody is supplied as cell culture supernatant diluted in tris buffered saline, pH 7.3-7.7, with 1% BSA and <0.1% sodium azide. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | CD19 antigen |
| Database Link | |
| Synonyms | B4; Leu-12; MGC12802 |
| Note | CD19 is present in both benign and malignant B-cells and has long been considered to be the most reliable surface marker of this lineage over a wide range of maturational stages. In normal lymphoid tissue, CD19 is observed in germinal centers, in mantle zone cells, and in scattered cells of the interfollicular areas. Anti-CD19 exhibits an overall immunoreactivity pattern similar to those of the antibodies against CD20 and CD22. However, in contrast to CD20, CD19 is also expressed in immature B-cells. Recently, Masir et al. have described the expression of CD19 in normal lymphoid tissue and its loss in B-cell neoplasms.Anti-CD19 positivity is seen in the vast majority of B-cell neoplasms commonly at a lower intensity than normal B-cell counterparts. Plasma cell neoplasms are nearly always negative, as are T-cell neoplasms. |
| Reference Data | |
| Protein Categories | ADC Targets, CAR-T Targets, CD Markers, Immune system diseases, Membrane Proteins |
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