OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

MRP4 (ABCC4) Rabbit Polyclonal Antibody

Be the first to review this product
SKU
TA327332
ABCC4 Rabbit Polyclonal Antibody
Size:
100 ul
Conjugation:
Unconjugated
  $410.00
3 Weeks*
Bulk/Customize

Frequently Bought Together (2)

TA811000S beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control 30 ul
$200.00
LY426242 Transient overexpression lysate of ATP-binding cassette, sub-family C (CFTR/MRP), member 4 (ABCC4), transcript variant 2 (as WB positive control) 100 ug
$665.00

View other "MRP4 or NM_001105515" antibodies

Specifications
Specifications
Product Data
Application ELISA, ICC/IF, IHC, WB
Recommended Dilution WB:1/500-1000;IHC:1/50-200
ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Buffer Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Storage Store at -20℃. Avoid freeze / thaw cycles.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 150kDa
Gene Name ATP binding cassette subfamily C member 4
Database Link
Background The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This family member plays a role in cellular detoxification as a pump for its substrate, organic anions. It may also function in prostaglandin-mediated cAMP signaling in ciliogenesis. Alternative splicing of this gene results in multiple transcript variants.
Synonyms MOAT-B; MOATB; MRP4
Reference Data
Protein Categories Membrane Proteins
Protein Families Druggable Genome, Ion Channels: Other, Transmembrane
Protein Pathways ABC transporters
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources

file-alt Citations

Supplementation With Curcumin Exhibits Nephroprotective Effects in Cisplatin-Induced Acute Kidney Injury
Zhang, Wang, Wang et al
Food Sci Nutr (2025) 13 (12), e71240 DOI: 10.1002/fsn3.71240
Cited by 6
AI Summary: In this study, OriGene products—specifically anti-MATE1 (TA381669) and anti-MRP4 (TA327332) antibodies—were used to assess the expression of renal transporters involved in evaluating curcumin’s protective effects against cisplatin-induced kidney injury.
Snippet: erature to reduce background (Shao et al. 2023). Subsequently, we incubated the above membranes with anti‐OAT3 (ThermoFisher, PA5102699), anti‐OCT2 (Novus Biologicals, NBP189417), anti‐MATE1 (ORIGENE, TA381669), anti‐MRP2 (Abcom, Ab203397), anti‐MRP4 (ORIGENE, TA327332), anti‐Kim1 (Novus Biologicals, NBP176701), anti‐NGAL (ThermoFisher, PA579591), anti‐Nrf2 (Santa Cruz Bio, sc722
FigureFigureFigure
Nephropathy induced by cisplatin results from mitochondrial disruption, impaired energy metabolism, altered expression of renal transporters, and accumulation of urinary toxins
Zhang, Zhang, Ma et al
J Trace Elem Med Biol (2024) 86, 127553 DOI: 10.1016/j.jtemb.2024.127553
Cited by 10
AI Summary: OriGene products contributed to this study by providing anti-MATE1 (TA381669) and anti-MRP4 (TA327332) antibodies, which were used to assess changes in renal transporter expression during cisplatin-induced nephrotoxicity.
Snippet: … Then the membranes were incubated with anti-OAT1 (Sigma-Aldrich, SAB2102177), anti-OAT3 (ThermoFisher, PA5102699), anti-OCT2 (Novus Biologicals, NBP189417), anti-MATE1 (ORIGENE, TA381669), anti-MRP2 (Abcom, Ab203397), anti-MRP4 (ORIGENE, TA327332), anti-BCRP (Abcom, ab 207732), and anti-β-actin antibodies overnight at 4°C. …
WB
The toxicity of cisplatin derives from effects on renal organic ion transporters expression and serum endogenous substance levels
Zhang, Li, Ma et al
Food Chem Toxicol (2024) 192, 114949 DOI: 10.1016/j.fct.2024.114949
Cited by 7
AI Summary: OriGene products, specifically the anti-MATE1 (TA381669) and anti-MRP4 (TA327332) antibodies, were used in this study to detect the expression of renal transporters involved in cisplatin-induced toxicity.
Snippet: Then the membranes were incubated with anti-OAT1 (Sigma-Aldrich, SAB2102177), anti-OAT3 (ThermoFisher, PA5102699), anti-OCT2 (Novus Biologicals, NBP189417), anti-MATE1 (ORIGENE, TA381669), anti-MRP2 (Abcom, Ab203397), anti-MRP4 (ORIGENE, TA327332), and anti-β-actin antibodies overnight at 4 °C. …
WB
Identification of a substrate of the renal tubular transporters for detecting drug-induced early acute kidney injury
Jin, Ma, Liu et al
Toxicol Sci (2024)
Cited by 2
AI Summary: In this study, OriGene’s anti-rMRP4 (TA327332) and anti-rMATE1 (TA381669) antibodies were used to detect the expression of renal tubular transporters, helping to elucidate their role in early acute kidney injury biomarker identification.
Snippet: purchased from Abcam Inc. Anti-rOCT2 (NBPI-89417) was purchased from Novus. Anti-rMRP4 (TA327332) and Anti-rMATE1 (TA381669) were purchased from Origene. Anti-β-actin (AF7018) was purchased from Affinity Biosciences. Methanol and acetonitrile were high-performance liquid chromatography (HPLC)-grade (Fish
Uric Acid Accumulation in the Kidney Triggers Mast Cell Degranulation and Aggravates Renal Oxidative Stress
Zhang, Cui, Zhou et al
Toxicology (2022) 483, 153387 DOI: 10.1016/j.tox.2022.153387
Cited by 34
AI Summary: In this study, the OriGene anti-MRP4 antibody (TA327332) was used to detect the expression of the urate transporter MRP4, helping to elucidate how uric acid accumulation affects renal transporter regulation and contributes to kidney injury.
Snippet: …The PVDF membrane was blocked with 5% skimmed milk (dissolved in TBS-T) for 1 h at room temperature and then incubated with anti-OAT1 (Sigma-Aldrich, SAB2102177), anti-OAT3 (ThermoFisher, PA5–102699), anti-MRP4 (OriGene, TA327332), anti-BCRP (Abcom, ab 207732), anti-URAT1 (Affinity, DF12340), anti-β-actin antibody at 4 ℃ overnight. …
WB
O-Sulfation disposition of curcumin and quercetin in SULT1A3 overexpressing HEK293 cells: the role of arylsulfatase B in cellular O-sulfation regulated by transporters
Pei, Dou, Zhang et al
Food Funct (2022)
Cited by 8
AI Summary: OriGene products—specifically the BCRP (TA322704), MRP4 (TA327332), and β-actin (TA328070) antibodies—were used in this study to detect and analyze transporter proteins involved in the O-sulfation and cellular excretion of curcumin and quercetin.
Snippet: BCRP (catalog number TA322704), MRP4 (catalog number TA327332), and β-actin (catalog number TA328070) were purchased from OriGene Technologies (Rockville, MD). …
Showing 1-6 of 14 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products