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Decorin (DCN) Rabbit Polyclonal Antibody

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SKU
TA327131
DCN Rabbit Polyclonal Antibody
Size:
100 ul
Conjugation:
Unconjugated
  $410.00
3 Weeks*
Bulk/Customize

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View other "Decorin or NM_001920" antibodies

Specifications
Specifications
Product Data
Application ELISA, ICC/IF, IHC, WB
Recommended Dilution WB,1:500 - 1:1000
IHC-P,1:50 - 1:200
IF/ICC,1:50 - 1:200
ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Buffer Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Storage Store at -20℃. Avoid freeze / thaw cycles.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 40kDa
Gene Name decorin
Database Link
Background This gene encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. This protein plays a role in collagen fibril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. This gene and the related gene biglycan are thought to be the result of a gene duplication. Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients.
Synonyms CSCD; DSPG2; PG40; PGII; PGS2; SLRR1B
Reference Data
Protein Categories Growth Factors, Intracellular Proteins, Nervous system Diseases, Secreated Proteins
Protein Families Druggable Genome, Secreted Protein
Protein Pathways TGF-beta signaling pathway
Reviews
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Documents
Resources

file-alt Citations

Cruciate Ligament Cell Sheets Can Be Rapidly Produced on Thermoresponsive poly(glycidyl ether) Coating and Successfully Used for Colonization of Embroidered Scaffolds
Zahn, Stöbener, Weinhart et al
Cells (2021) 10 (4) DOI: 10.3390/cells10040877
Cited by 7
AI Summary: In this study, the OriGene rabbit-anti-human decorin antibody was used to detect decorin expression, helping assess ligamentocyte phenotype and extracellular matrix deposition during ligament cell sheet formation and scaffold colonization.
Snippet: Y DILUTION collagen type I goat-anti-human (COL1A1 chain), Abcam, Cambridge, UK 1:50 donkey-anti-goat;cy 3, Dianova GmbH, Hamburg, Germany 1:200 decorin rabbit-anti-human, OriGene Rockville, MD, USA 1:50 donkey-anti-rabbit;Alexa-Fluor488, ThermoFisher Scientific Inc., Germany 1:200 phalloidin Alexa- Fluor488 stains filamentous (F-) actin, Santa Cruz Bio
FigureFigureFigure
IF
The Effect of Lecithins Coupled Decorin Nanoliposomes on Treatment of Carbon Tetrachloride-Induced Liver Fibrosis
Chen, Zhu, Liang et al
Biomed Res Int (2020) 2020, 8815904 DOI: 10.1155/2020/8815904
Cited by 9
AI Summary: In this study, OriGene products including antibodies against α-smooth muscle actin (α-SMA), collagen type I alpha 1 (COL1A1), and transforming growth factor-β (TGF-β) were used for Western blot and immunofluorescence analyses to assess the effects of PC-DCN nanoliposomes on liver fibrosis.
FigureFigureFigure
The Effect of Lecithins Coupled Decorin Nanoliposomes on Treatment of Carbon Tetrachloride-Induced Liver Fibrosis
Chen, Zhu, Liang et al
BioMed Research International (2020) 2020, 1-10 DOI: 10.1155/2020/8815904
Cited by 9
AI Summary: In this study, the OriGene anti-DCN antibody (TA327131) was used for Western blot analysis to detect decorin protein expression, contributing to the evaluation of the antifibrotic effects of PC-DCN nanoliposomes in liver fibrosis models.
Snippet: anti-COL1A1 (Abcam;ab34710;1 : 1000), anti-TGF-β (Proteintech;18978;1 : 1000), and anti-DCN antibodies (Origene;TA327131;1 : 1000) overnight at 4°C,
WB
Showing 1-3 of 3 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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