IL7R alpha (IL7R) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | ELISA, WB |
|---|---|
| Recommended Dilution | WB,1:500 - 1:1000 ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. |
| Reactivity | Human, Mouse |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Buffer | Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |
| Concentration | lot specific |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 52kDa |
| Gene Name | interleukin 7 receptor |
| Database Link | |
| Background | The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found. |
| Synonyms | CD127; CDW127; IL-7R-alpha; IL7RA; ILRA |
| Reference Data | |
| Protein Categories | CD Markers, Cytokines, Immune system diseases, Intracellular Proteins, Membrane Proteins |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
| Protein Pathways | Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway, Primary immunodeficiency |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
Expression of Foxp3 and interleukin-7 receptor and clinicopathological characteristics of patients with diffuse large B-cell lymphoma
Zhao, Cui, Feng et al
Oncol Lett (2020) 19 (4), 2755-2764 DOI: 10.3892/ol.2020.11374
Zhao, Cui, Feng et al
Oncol Lett (2020) 19 (4), 2755-2764 DOI: 10.3892/ol.2020.11374
Cited by 25
AI Summary: In this study, OriGene’s anti-Foxp3 antibody (catalog no. TA500628) and anti-IL-7R antibody (catalog no. TA506772) were used for immunohistochemical detection of Foxp3 and IL-7R expression in diffuse large B-cell lymphoma tissue samples, enabling analysis of their association with clinicopathological features and patient prognosis.
Showing 1-1 of 1 papers.
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