VDAC1 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | ELISA, IHC, WB |
|---|---|
| Recommended Dilution | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 ELISA,Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Buffer | Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |
| Concentration | lot specific |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 31kDa |
| Gene Name | voltage dependent anion channel 1 |
| Database Link | |
| Background | This gene encodes a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane. The encoded protein facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions. This protein also forms channels in the plasma membrane and may be involved in transmembrane electron transport. Alternate splicing results in multiple transcript variants. Multiple pseudogenes of this gene are found on chromosomes 1, 2 3, 6, 9, 12, X and Y. |
| Synonyms | PORIN; VDAC-1 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Families | Ion Channels: Other |
| Protein Pathways | Calcium signaling pathway, Huntington's disease, Parkinson's disease |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
Metabolic Reprogramming of Pathogenic CD4+ T Helper Cells Attenuates Inflammatory Bowel Disease Pathogenesis
Mishra, Abdelrahman, Davidson et al
bioRxiv (2025)
Mishra, Abdelrahman, Davidson et al
bioRxiv (2025)
13-Methylpalmatine improves myocardial infarction injury by inhibiting CHOP-mediated cross-talk between endoplasmic reticulum and mitochondria
Jiang, Wen, Mao et al
Biomed Pharmacother (2024) 179, 117342 DOI: 10.1016/j.biopha.2024.117342
Jiang, Wen, Mao et al
Biomed Pharmacother (2024) 179, 117342 DOI: 10.1016/j.biopha.2024.117342
Cited by 9
AI Summary: OriGene’s VDAC1 antibody (TA326858) was used in this study to detect VDAC1 protein expression, helping to elucidate the role of ER-mitochondrial Ca2+ transfer in the protective effects of 13-Methylpalmatine against myocardial infarction injury.
Snippet: BCL-2 (CPA1095, Cohesion Biosciences, USA, 1:1000), BAX (CY5059, Abways, Beijing, China, 1:1000), IP3R (CY6963, Abways, Beijing, China, 1:1000), VDAC1 (TA326858, OriGene Technologies, USA, 1:1000), and GAPDH (AB0036, Abways, China, 1:3000) at 4°C overnight. Subsequently, the membranes were incubated with secondary antibodies for 1 h at room temperature
Chimeric antigen receptor-induced antigen loss protects CD5.CART cells from fratricide without compromising on-target cytotoxicity
Ma, Woods, Burkhardt et al
Cell Rep Med (2024) 5 (7), 101628 DOI: 10.1016/j.xcrm.2024.101628
Ma, Woods, Burkhardt et al
Cell Rep Med (2024) 5 (7), 101628 DOI: 10.1016/j.xcrm.2024.101628
Cited by 14
AI Summary: OriGene's Human soluble CD5 ELISA Kit (Cat#EA100720) was used in this study to measure soluble CD5 levels, contributing to the evaluation of CD5 protein expression and internalization in T cells.
Snippet: Plus Micro Kit Qiagen Cat#74034 SuperScript III First-Strand Synthesis SuperMix Invitrogen Cat#18080-400 HiScribe T7 New England Biosciences Cat#E2040S Human soluble CD5 ELISA Kit OriGene Cat#EA100720 CD3 Microbeads, human Miltenyi Biotec Cat#130-050-101 Chromium Next GEM Single Cell 5′ Kit v2 10x Genomics Cat#1000263 5′ Feature Barcode Kit 10x Genomics
Interleukin 21 Drives a Hypermetabolic State and CD4+ T-Cell–Associated Pathogenicity in Chronic Intestinal Inflammation
Bamidele, Mishra, Ramos et al
Gastroenterology (2024)
Bamidele, Mishra, Ramos et al
Gastroenterology (2024)
Cited by 18
AI Summary: OriGene’s anti-human/mouse/rat VDAC1 antibody (catalog number TA326858) was used in this study to detect VDAC1 protein, contributing to the analysis of mitochondrial function in CD4+ T cells during chronic intestinal inflammation.
Snippet: Anti-human/mouse/rat VDAC1 (lot number 3507477001) Origene Catalog number TA326858 Anti-human/mouse/rat/monkey GRP75 Abcam Catalog number ab2799 Anti-human/mouse/rat/monkey TOM20 Cell Signaling Catalog number 42406S Anti-human/mouse/rat IP3R-I Santa Cruz Catalog number sc-271197 Anti-human/mouse/rat phospho b-catenin-serine 37 PetroTech Catalog number 28776-1-AP Anti-human/mouse/rat phospho b-catenin-serine 33 PetroTech Catalog number 80067-1-RR Anti-human/mouse/rat b-catenin PetroTech Catalog number 66379-1-Ig Alexa Fluor 488 anti-human FOXP3 (clone 259D) BioLegend Catalog number 32
Showing 1-4 of 4 papers.
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