Caveolin 1 (CAV1) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | WB |
|---|---|
| Recommended Dilution | WB: 1:500-1:2000 |
| Reactivity | Human, Mouse, Rat |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | The antiserum was produced against A synthesized peptide derived from human Caveolin-1 |
| Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration | lot specific |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 23 kDa |
| Gene Name | caveolin 1 |
| Database Link | |
| Background | caveolin-1 May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Involved in the costimulatory signal essential for T-cell receptor (TCR)- mediated T-cell activation. |
| Synonyms | BSCL3; CGL3; LCCNS; MSTP085; PPH3; VIP21 |
| Reference Data | |
| Protein Categories | Cardiovascular diseases, Cytokines, Growth Factors, Intracellular Proteins, Membrane Proteins |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Focal adhesion, Viral myocarditis |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
Deletion of integrin linked kinase in endothelial cells results in defective RTK signaling caused by caveolin 1 mislocalization
Malan, Elischer, Hesse et al
Development (2013) 140 (5), 987-95 DOI: 10.1242/dev.091298
Malan, Elischer, Hesse et al
Development (2013) 140 (5), 987-95 DOI: 10.1242/dev.091298
Cited by 23
AI Summary: In this study, OriGene’s Caveolin 1-EGFP fusion protein was used to investigate the localization and dynamics of caveolin 1 in endothelial cells, revealing that ILK deletion disrupts caveolin 1 positioning and impairs receptor tyrosine kinase signaling.
Showing 1-1 of 1 papers.
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