Proprotein Convertase 2 (PCSK2) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | FC, IF, IHC, WB |
|---|---|
| Recommended Dilution | WB:1/1000, IHC-P:1/50-200, IF:1/10-50, FC:1/10-50 |
| Reactivity | Human, Mouse |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | This PCSK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 87-116 amino acids from the N-terminal region of human PCSK2. |
| Specificity | This PCSK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 87-116 amino acids from the N-terminal region of human PCSK2. |
| Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| Concentration | lot specific |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 70.6 kDa |
| Gene Name | proprotein convertase subtilisin/kexin type 2 |
| Database Link | |
| Background | PCSK2 belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This protein is a proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. The protein is also known to cleave proopiomelanocortin, proenkephalin, prodynorphin and proluteinizing-hormone-releasing hormone. |
| Synonyms | NEC-2; NEC 2; NEC2; PC2; SPC2 |
| Reference Data | |
| Protein Families | Druggable Genome, Protease, Secreted Protein |
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