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Ceruloplasmin (CP) Rabbit Polyclonal Antibody

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SKU
TA324926
CP Antibody (Center)
Size:
400 ul
Conjugation:
Unconjugated
  $645.00
2 Weeks*
Bulk/Customize

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Specifications
Specifications
Product Data
Application FC, IHC, WB
Recommended Dilution WB:1/2000, IHC-P:1/50-200, FC:1/10-50
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen This CP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 547-577 amino acids from the Central region of human CP.
Specificity This CP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 547-577 amino acids from the Central region of human CP.
Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Concentration lot specific
Purification Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Predicted Protein Size 122.2 kDa
Gene Name ceruloplasmin (ferroxidase)
Database Link
Background CP is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe(II)transferrin to Fe(III) transferrin. Mutations in this protein cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities.
Synonyms CP-2
Reference Data
Protein Families Druggable Genome
Protein Pathways Porphyrin and chlorophyll metabolism
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Documents
Resources

file-alt Citations

Active compounds of herbs ameliorate impaired cognition in APP/PS1 mouse model of Alzheimer's disease
Yu, An, Shao et al
Aging (Albany NY) (2019) 11 (23), 11186-11201 DOI: 10.18632/aging.102522
Cited by 31
AI Summary: In this study, the Ceruloplasmin antibody from OriGene was used to assess changes in iron metabolism proteins in the brains of Alzheimer's disease model mice, contributing to the evaluation of how herbal compounds ameliorate cognitive impairment.
Snippet: DMT1 with IRE (#NRAMP21-A;1:2,000) and DMT1 without IRE (#NRAMP23-A;1:2,000) from Alpha Diagnostics International;Transferrin antibody (N3C3;1:250) from GeneTex;TfR1 (1:100) from Thermo;FPN1 (1: 2,000;#MTP11-A) from Alpha Diagnostics International, Ceruloplasmin (1:50) from Origene;Hephaestin (1:200) from Alpha Diagnostics International;Ferritin(1:200) from Abcam;Hepcidin (1:50) from Abcam. On the...
FigureFigureFigure
IHC
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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