HAND2 Rabbit Polyclonal Antibody [Clone ID: RB36759]
Specifications
| Product Data | |
| Clone Name | RB36759 |
|---|---|
| Application | IF, WB |
| Recommended Dilution | IF 1:10~50 WB 1:1000 |
| Reactivity | Chicken, Human (Predicted: Mouse, Rat, Xenopus) |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | This HAND2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-110 amino acids from the Central region of human HAND2. |
| Specificity | This HAND2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-110 amino acids from the Central region of human HAND2. |
| Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| Concentration | lot specific |
| Purification | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Shelf life: one year from despatch. |
| Shipping | Blue Ice |
| Predicted Protein Size | 23666 kDa |
| Gene Name | heart and neural crest derivatives expressed 2 |
| Database Link | |
| Background | The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, this transcription factor plays an important role in limb and branchial arch development. |
| Synonyms | bHLHa26; dHand; DHAND2; Hed; Thing2 |
| Reference Data | |
| Protein Families | Druggable Genome |
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