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beta TRCP2 (FBXW11) Rabbit Polyclonal Antibody [Clone ID: RB18056]

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SKU
TA324389
FBXW11 Antibody (Center)
Size:
400 ul
Conjugation:
Unconjugated
  $645.00
5 Days*
Bulk/Customize

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View other "beta TRCP2 or NM_012300" antibodies

Specifications
Specifications
Product Data
Clone Name RB18056
Application FC, IHC, WB
Recommended Dilution WB 1:1000
IHC-P 1:50~100
FC 1:10~50
Reactivity Human (Predicted: Mouse)
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen This FBXW11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-196 amino acids from the Central region of human FBXW11.
Specificity This FBXW11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-196 amino acids from the Central region of human FBXW11.
Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Concentration lot specific
Purification Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Predicted Protein Size 62091 kDa
Gene Name F-box and WD repeat domain containing 11
Database Link
Background This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.
Synonyms BTRC2; BTRCP2; FBW1B; Fbw11; FBXW1B; Hos
Reference Data
Protein Families Druggable Genome
Protein Pathways Hedgehog signaling pathway, Oocyte meiosis, Ubiquitin mediated proteolysis, Wnt signaling pathway
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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