Folate Binding Protein (FOLR1) Rabbit Polyclonal Antibody

SKU
TA324367
FOLR1 Antibody (N-term)
  $645.00
2 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Application FC, WB
Recommended Dilution WB:1/1000, FC:1/10-50
Reactivity Human
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen This FOLR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-68 amino acids from the N-terminal region of human FOLR1.
Specificity This FOLR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-68 amino acids from the N-terminal region of human FOLR1.
Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Concentration lot specific
Purification Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Predicted Protein Size 29.8 kDa
Gene Name folate receptor 1 (adult)
Database Link
Background The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene.
Synonyms FBP; FOLR
Reference Data
Protein Families Druggable Genome, Secreted Protein, Transmembrane
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Documents
Resources

file-alt Citations

Targeted Delivery of Nanoparticulate Cytochrome C into Glioma Cells Through the Proton-Coupled Folate Transporter
Kucheryavykh, Davila, Ortiz-Rivera et al
Biomolecules (2019) 9 (4) DOI: 10.3390/biom9040154
AI Summary: OriGene products contributed to this study by providing the rabbit polyclonal anti-SLC46A1 antibody (#TA334591) and anti-FOLR1 antibody (#TA324367), which were used to detect and analyze the expression of PCFT and FOLR1 in glioma cells.
Snippet: serum/5% normal horse serum (Vector lab., Burlingame, CA, USA) in PBS containing 0.3% Triton X-100 and 0.05% phenylhydrazine for 30 min and incubated with rabbit polyclonal anti-SLC46A1 or anti-FOLR1 antibody (# TA334591, #TA324367, OriGene Technologies View as HTML
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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