Nck (NCK1) Rabbit Polyclonal Antibody

SKU
TA324087
Anti-NCK1 Rabbit Polyclonal Antibody
  $305.00
In Stock*
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Specifications
Specifications
Product Data
Application IHC, WB
Recommended Dilution WB: 500-2000
WB positive control: Hela cells
IHC: 10-50
Positive control: Human lung cancer
Predicted cell location: Cytoplasm
Reactivity Human, Mouse
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein corresponding to a C terminal 300 amino acids of human NCK adaptor protein 1
Buffer PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 43 kDa
Gene Name NCK adaptor protein 1
Database Link
Background The protein encoded by this gene is one of the signaling and transforming proteins containing Src homology 2 and 3 (SH2 and SH3) domains. It is located in the cytoplasm and is an adaptor protein involved in transducing signals from receptor tyrosine kinases to downstream signal recipients such as RAS. Alternatively spliced transcript variants encoding different isoforms have been found.
Synonyms NCK; nck-1; NCKalpha
Reference Data
Protein Categories Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways Axon guidance, ErbB signaling pathway, Pathogenic Escherichia coli infection, T cell receptor signaling pathway
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