Filaggrin (FLG) Rabbit Polyclonal Antibody

SKU TA323075

Anti-FLG Rabbit Polyclonal Antibody

Product Data

• Application: IHC
• Recommended Dilution: IHC: 25-100; Positive control: Human cervical cancer; Predicted cell location: Cytoplasm
• Reactivity: Human
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 1215-1229 amino acids of human filaggrin
• Buffer: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: filaggrin
• Database Link:
  NP_002007
  P20930
• Background: The protein encoded by this gene is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor; profilaggrin (consisting of multiple filaggrin units of 324 aa each); which is localized in keratohyalin granules; and is subsequently proteolytically processed into individual functional filaggrin molecules. Mutations in this gene are associated with ichthyosis vulgaris.
• Synonyms: ATOD2

Reference Data

• Protein Families: Druggable Genome