Deltex (DTX1) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC |
|---|---|
| Recommended Dilution | IHC: 25-100 Positive control: Human brain Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 50-64 amino acids of Human deltex homolog 1 (Drosophila) |
| Buffer | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | deltex 1 |
| Database Link | |
| Background | Protein deltex-1 is a protein that in humans is encoded by the DTX1 gene. Studies in Drosophila have identified this gene as encoding a positive regulator of the Notch-signaling pathway. The human gene encodes a protein of unknown function; however; it may play a role in basic helix-loop-helix transcription factor activity. DTX1 has been shown to interact with EP300. Functions as an ubiquitin ligase protein in vivo; mediating ubiquitination and promoting degradation of MEKK1; suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity. |
| Synonyms | hDx-1 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | Notch signaling pathway |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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