Laminin (LAMA1) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC |
|---|---|
| Recommended Dilution | IHC: 50-200 Positive control: Human brain Predicted cell location: Cytoplasm |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 1606-1620 amino acids of Human laminin, alpha 1 |
| Buffer | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | laminin subunit alpha 1 |
| Database Link | |
| Background | Laminin subunit alpha-1?is a?protein?that in humans is encoded by the?LAMA1?gene. Laminin is a complex glycoprotein; consisting of three different polypeptide chains (alpha; beta; gamma); which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end. Alpha-1 is a subunit of laminin-1 (laminin-111 or EHS laminin) and laminin-3 (laminin-121 or S-laminin). Binding to cells via a high affinity receptor; laminin is thought to mediate the attachment; migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. |
| Synonyms | LAMA; PTBHS; S-LAM-alpha |
| Reference Data | |
| Protein Categories | Secreated Proteins |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS |
| Protein Pathways | ECM-receptor interaction, Focal adhesion, Pathways in cancer, Small cell lung cancer |
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