SELS (SELENOS) Rabbit Polyclonal Antibody

SKU TA322291

Anti-VIMP Rabbit Polyclonal Antibody

Product Data

• Application: IHC
• Recommended Dilution: IHC: 25-100; Positive control: Human brain; Predicted cell location: Cytoplasm, Endoplasmic reticulum membrane
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region derived from 98-112 amino acids of human VCP-interacting membrane protein
• Buffer: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: VCP interacting membrane selenoprotein
• Database Link:
  NP_060915
  Q9BQE4
• Background: This gene encodes a selenoprotein; which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure; the sec insertion sequence (SECIS); that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Studies suggest that this protein may regulate cytokine production; and thus play a key role in the control of the inflammatory response. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
• Synonyms: AD-015; ADO15; SBBI8; SELS; SEPS1

Reference Data

• Protein Families: Druggable Genome