SLC22A6 Rabbit Polyclonal Antibody
Product Data | |
Application | IHC, WB |
---|---|
Recommended Dilution | WB: 500-2000 WB positive control: Human fetal kidney tissue IHC: 50-200 Positive control: Human colon cancer Predicted cell location: Cytoplasm |
Reactivity | Human, Rat |
Antibody Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Synthetic peptide corresponding to a region derived from 551-563 amino acids of Human solute carrier family 22 (organic anion transporter), member 6 |
Buffer | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Shipping | Blue Ice |
Predicted Protein Size | 56 kDa |
Gene Name | solute carrier family 22 member 6 |
Database Link | |
Background | The protein encoded by this gene is involved in the sodium-dependent transport and excretion of organic anions; some of which are potentially toxic. The encoded protein is an integral membrane protein and may be localized to the basolateral membrane. Four transcript variants encoding four different isoforms have been found for this gene. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate; ketoglutarate; etc). Mediates the sodium-independent uptake of 2;3-dimercapto-1-propanesulfonic acid (DMPS) By similarity. |
Synonyms | HOAT1; OAT1; PAHT; ROAT1 |
Reference Data | |
Protein Families | Transmembrane |
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