Amphiphysin (AMPH) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC, WB |
|---|---|
| Recommended Dilution | WB: 500-2000 WB positive control: Mouse lung tissue IHC: 50-200 Positive control: Human ovarian cancer Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Fusion protein corresponding to C terminal 250 amino acids of human amphiphysin |
| Buffer | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Concentration | lot specific |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 76 kDa |
| Gene Name | amphiphysin |
| Database Link | |
| Background | This gene encodes a protein associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff-man syndrome who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional splice variants have been described; but their full length sequences have not been determined. A pseudogene of this gene is found on chromosome 11. |
| Synonyms | AMPH1 |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Families | Secreted Protein |
| Protein Pathways | Fc gamma R-mediated phagocytosis |
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