Ku70 (XRCC6) Rabbit Polyclonal Antibody

SKU
TA321351
Anti-XRCC6 Rabbit Polyclonal Antibody
  $305.00
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Specifications
Specifications
Product Data
Application IHC
Recommended Dilution IHC: 10-50
Positive control: Human colon cancer
Predicted cell location: Nucleus
Reactivity Human, Mouse
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein corresponding to a C terminal 300 amino acids of human X-ray repair complementing defective repair in Chinese hamster cells 6
Buffer PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name X-ray repair complementing defective repair in Chinese hamster cells 6
Database Link
Background The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair; transposition; and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
Synonyms CTC75; CTCBF; G22P1; KU70; ML8; TLAA
Reference Data
Protein Categories Intracellular Proteins
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Non-homologous end-joining
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