TSH Receptor (TSHR) Rabbit Polyclonal Antibody

SKU
TA321117
Anti-TSHR Rabbit Polyclonal Antibody
  $305.00
4 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Application IHC
Recommended Dilution IHC: 25-100
Positive control: Human liver cancer
Predicted cell location: Cytoplasm
Reactivity Human
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Fusion protein corresponding to a region derived from 21-253 amino acids of human thyroid stimulating hormone receptor
Buffer PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name thyroid stimulating hormone receptor
Database Link
Background The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin; and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene.
Synonyms CHNG1; hTSHR-I; LGR3
Reference Data
Protein Categories Endocrine and metabolic diseases, GPCR, Intracellular Proteins, Membrane Proteins
Protein Families Druggable Genome, GPCR, Transmembrane
Protein Pathways Autoimmune thyroid disease, Neuroactive ligand-receptor interaction
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Documents
Resources

file-alt Citations

Characterization of the sex-dependent myocardial S-nitrosothiol proteome
Shao, Fallica, Casin et al
Am. J. Physiol. Heart Circ. Physiol. (2015)
Cited by 53
AI Summary: In this study, the OriGene GSNO-R antibody (catalog number TA3211174) was used to detect GSNO reductase protein levels, contributing to the characterization of sex-dependent differences in myocardial S-nitrosothiol proteomes.
Snippet: Page 13. 13 Biotechnology), iNOS (1:250;Santa Cruz Biotechnology), GSNO-R (1:1000;Origene, 253 TA3211174), SERCA2a (1:1000;Santa Cruz Biotechnology), aconitase (1:1000;Cell 254 Signaling, 6922), or GAPDH (1:1000;Santa Cruz Biotechnology). ... Cite SaveSaving
WB
Showing 1-1 of 1 papers.
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