KCNK12 Rabbit Polyclonal Antibody

SKU
TA319968
Rabbit Polyclonal KCNK12 Antibody
  $640.00
5 Days*
Bulk/Customize
Specifications
Specifications
Product Data
Application IF, IHC, WB
Recommended Dilution WB: 0.5 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen KCNK12 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human KCNK12.
Buffer KCNK12 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration 1ug/ul
Purification KCNK12 Antibody is affinity chromatography purified via peptide column.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name potassium two pore domain channel subfamily K member 12
Database Link
Background KCNK12 Antibody: KCNK13 and KCNK12 (also known as THIK1 and 2) are the first two members of a novel two pore-forming P domains K+ channels subfamily. The pore loop domain, a highly conserved region common to all potassium channels, is involved in determining potassium ion selectivity. Members of this family are all characterized by four transmembrane domains and may function to help influence the resting membrane potential of cells. KCNK12 is expressed mainly in the brain and lung, but also observed in the kidneys, heart and skeletal muscle. KCNK12 is closely related to KCNK13 (58% identity at the amino acid level), but could not yet been functionally expressed in vitro and may require other proteins to become active.
Synonyms K2p12.1; THIK-2; THIK2
Reference Data
Protein Categories Membrane Proteins
Protein Families Druggable Genome, Ion Channels: Potassium, Transmembrane
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