FBXW11 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | ELISA, IF, WB |
|---|---|
| Recommended Dilution | WB: 1:200 to 1:1,000 IF: User Optimized ELISA: 1:10,000 – 1:100,000 |
| Reactivity | Human, Mouse |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a region near the N-terminal of human βTrCP2 protein. |
| Specificity | This product was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody reacts with human βTrCP2 protein. A BLAST analysis was used to suggest cross-reactivity with βTrCP2 from human, mouse, dog, bovine, chimpanzee, chicken and horse based on a 100% homology with the immunizing sequence. Cross-reactivity with βTrCP2 from other sources has not been determined. |
| Buffer | 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 Stabilizer: None Preservative: 0.01% (w/v) Sodium Azide |
| Concentration | 0.8 mg/mL - lot specific |
| Conjugation | Unconjugated |
| Storage | Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. |
| Stability | Expiration date is one (1) year from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | F-box and WD repeat domain containing 11 |
| Database Link | |
| Background | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons. |
| Synonyms | rabbit anti-beta TrCP2 antibody, rabbit anti-BTRCP2 antibody, F-box/WD repeat-containing protein 11, beta Transducin Repeat Containing Protein 2 antibody, BTRC2 antibody, F-box and WD-40 Domain Protein 1B antibody, F-box Protein FBW1B antibody, FBW1B antibody, FBXW1B antibody, Homologous to Slimb protein, HOS, FBXW11 |
| Note | This affinity purified antibody has been tested for use in ELISA and western blotting. |
| Reference Data | |
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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