ELOVL5 Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC, WB |
|---|---|
| Recommended Dilution | WB: 1:500~1:3000, IHC: 1:50~1:100, ELISA: 1:40000 |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | The antiserum was produced against synthesized peptide derived from internal of human ELOVL5. |
| Buffer | Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration | lot specific |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | ELOVL fatty acid elongase 5 |
| Database Link | |
| Synonyms | dJ483K16.1; HELO1; SCA38 |
| Note | ELOVL5 antibody detects endogenous levels of total ELOVL5 protein. |
| Reference Data | |
| Protein Categories | Intracellular Proteins, Membrane Proteins, Nervous system: Neurodegenerative diseases |
| Protein Families | Transmembrane |
| Protein Pathways | Biosynthesis of unsaturated fatty acids |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
The impact of PUFA on cell responses: Caution should be exercised when selecting PUFA concentrations in cell culture
Mbarik, Biam, Robichaud et al
Prostaglandins Leukot Essent Fatty Acids (2020) 155, 102083 DOI: 10.1016/j.plefa.2020.102083
Mbarik, Biam, Robichaud et al
Prostaglandins Leukot Essent Fatty Acids (2020) 155, 102083 DOI: 10.1016/j.plefa.2020.102083
Cited by 21
AI Summary: In this study, OriGene products—including the DGAT1 (Cat# SR311204) and DGAT2 (Cat# SR304431) shRNA plasmids—were used to selectively inhibit DGAT1 and DGAT2 enzymes, helping to demonstrate that DGAT1 inhibition enhanced PUFA-induced cytotoxicity, thereby clarifying the protective role of triglyceride formation in cell responses to PUFA.
Impact of 17β-HSD12, the 3-ketoacyl-CoA reductase of long-chain fatty acid synthesis, on breast cancer cell proliferation and migration
Tsachaki, Strauss, Dunkel et al
Cell. Mol. Life Sci. (2019) 77 (6), 1153-1175 DOI: 10.1007/s00018-019-03227-w
Tsachaki, Strauss, Dunkel et al
Cell. Mol. Life Sci. (2019) 77 (6), 1153-1175 DOI: 10.1007/s00018-019-03227-w
AI Summary: OriGene’s ELOVL5 antibody was used in this study to investigate the role of long-chain fatty acid synthesis in breast cancer cell proliferation and migration.
Snippet: Caspase-3 (Cas-3) 0.1 μg/ml (Cell Signaling Technology, #9665), cleaved Cas-3 0.1 μg/ml (Cell Signal- ing Technology, #9664), Bcl-2 0.1 μg/ml (Cell Signaling Technology, #2870), Bax 0.1 μg/ml (Cell Signaling Technol- ogy, #5023), and ELOVL5 1 μg/ml (Origene
Polyunsaturated fatty acid elongation and desaturation in activated human T cells: ELOVL5 is the key elongase
Robichaud, Munganyiki, Boilard et al
J. Lipid Res. (2018)
Robichaud, Munganyiki, Boilard et al
J. Lipid Res. (2018)
Showing 1-3 of 3 papers.
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