CHREBP (MLXIPL) Rabbit Polyclonal Antibody

SKU
TA309750
Rabbit Polyclonal CHREBP Antibody
  $680.00
2 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Application ChIP, ICC/IF, IHC, Immunoblotting, IP, SDS-PAGE, WB
Recommended Dilution Chromatin Immunoprecipitation (ChIP): 1:10-1:500, Immunohistochemistry: 1:100, Western Blot: 1:1000, Immunohistochemistry-Paraffin: 1:100, SDS-Page, Chromatin Immunoprecipitation: 1:10 - 1:500, Gel Super Shift Assays, Immunoblotting, Knockout Validated, Immunoprecipitation: 1:10 - 1:500, Immunocytochemistry/ Immunofluorescence: 1:100 - 1:500
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Clonality Polyclonal
Immunogen An C-terminal synthetic peptide made to the human ChREBP protein sequence (between residues 800-852). NCBI# NP_116569.1, isoform 1/alpha
Buffer in Tris-citrate/phosphate, pH 7-8 and 0.01% Sodium Azide
Concentration lot specific
Purification Immunogen affinity purified
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name MLX interacting protein like
Database Link
Synonyms bHLHd14; CHREBP; MIO; MLX; MONDOB; WBSCR14; WS-bHLH
Reference Data
Protein Categories Intracellular Proteins, Transciption Factors
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Documents
Resources

file-alt Citations

Baicalein Prevents Fructose-Induced Hepatic Steatosis in Rats: In the Regulation of Fatty Acid De Novo Synthesis, Fatty Acid Elongation and Fatty Acid Oxidation
Li, Zhang, Wang et al
Front Pharmacol (2022) 13, 917329 DOI: 10.3389/fphar.2022.917329
Cited by 49
AI Summary: In this study, OriGene's anti-ChREBP antibody (CAT: TA309750) was used to detect ChREBP protein levels, helping to elucidate the molecular mechanisms by which baicalein prevents fructose-induced hepatic steatosis in rats.
Snippet: bridge, England). The antibodies for ELOVL6 (CAT: 21160-1-AP) and Lamin B1 (CAT: 12987-1-AP) were from Proteintech (Rosemont, United States), Antibody against ChREBP (CAT: TA309750) was obtained from OriGene Technologies (Rockville, MD, United States), and Antibody against SREBP1c (CAT: sc-13551), PPARα (CAT: sc-398394) and SCD1 (CAT: sc-81776) were purchased from Santa Cruz Biotechnology (Santa
FigureFigureFigure
WB
6-gingerol ameliorates age-related hepatic steatosis: Association with regulating lipogenesis, fatty acid oxidation, oxidative stress and mitochondrial dysfunction
Li, Wang, Yao et al
Toxicol. Appl. Pharmacol. (2018) 362, 125-135 DOI: 10.1016/j.taap.2018.11.001
AI Summary: OriGene products contributed to this study by providing the primary rabbit polyclonal antibody against ChREBP, which was used to assess protein expression related to lipid metabolism in the liver.
Snippet: The membranes were blocked with 5% skim milk for 1 h at room temperature and then incubated with the following primary antibodies overnight at 4 °C. The primary rabbit polyclonal antibodies were ChREBP (OriGene Technologies, Rockville, MD, USA), DGAT-2
WB
Oncogene-dependent addiction to carbohydrate-responsive element binding protein in hepatocellular carcinoma
Ribback, Che, Pilo et al
Cell Cycle (2018) 17 (12), 1496-1512 DOI: 10.1080/15384101.2018.1489182
AI Summary: OriGene’s human ChREBP-targeting siRNA (ID # SR309520) was used to suppress ChREBP expression in HCC cell lines, enabling the authors to study the effects of ChREBP silencing on cancer cell proliferation and apoptosis.
Snippet: For silencing studies, HLE and AKT/Ras cells were transfected with 50 nM siRNA targeting either human (ID # SR309520;Origene Technologies) or mouse (ID # s81679;Life Technologies, Grand Island, NY) ChREBP gene. A scrambled small interfering RNA (siRNA;ID # 4390846;Life Technologies) was used as negative control. Experiments were repeated at least three times in triplicate
Showing 1-3 of 3 papers.
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