Nefl Chicken Polyclonal Antibody
Specifications
| Product Data | |
| Application | WB |
|---|---|
| Recommended Dilution | WB: 1:10,000, IF: 1:5,000 |
| Reactivity | Rat |
| Antibody Host | Chicken |
| Isotype | IgY |
| Clonality | Polyclonal |
| Immunogen | Preparation of bovine spinal cord NF-L |
| Buffer | total IgY fraction in PBS + 10 mM NaN3. |
| Purification | Total IgY fraction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 68 kDa |
| Gene Name | neurofilament, light polypeptide |
| Database Link | |
| Background | Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. provided by RefSeq |
| Synonyms | CMT1F; CMT2E; FLJ53642; neurofilament-light; NF-L; NF68; NFL |
| Reference Data | |
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