Actin (ACTA1) Rabbit Polyclonal Antibody

CAT#: TA308837

Rabbit polyclonal anti-ACTA1(alpha Actin, skeletal muscle) antibody, Loading control

Product Images

Sample (30 ug of whole cell lysate). A: NIH-3T3. B: JC. C: BCL-1. D: C2C12. 10% SDS PAGE. TA308837 diluted at 1:5000.

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  Sample (30 ug of whole cell lysate). A:Raji. 10% SDS PAGE. TA308837 diluted at 1:1000

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  Immunohistochemical analysis of paraffin-embedded Skeletal Muscle, using alpha Actin (skeletal muscle) (TA308837) antibody (10 ug/ml).

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB 1:1000 - 1:10000, IHC:1:100 - 1:1000
• Reactivities: Human, Mouse (Predicted: Rat, Pig, Chicken, Bovine)
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 377 of alpha Actin (skeletal muscle)
• Formulation: 1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 42 kDa
• Gene Name: actin, alpha 1, skeletal muscle
• Database Link:
  NP_001091
  Entrez Gene 11459 MouseEntrez Gene 29437 RatEntrez Gene 58 Human
  UniProt ID P68133
• Background: The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. [provided by RefSeq]
• Synonyms: ACTA; ASMA; CFTD; CFTD1; CFTDM; MPFD; NEM1; NEM2; NEM3; SHPM
• Note: Seq homology of immunogen across species: Rat (100%), Pig (100%), Chicken (100%), Bovine (100%)

Reference Data

• Protein Families: Stem cell - Pluripotency