RAE1 Rabbit Polyclonal Antibody

SKU TA308264

Rabbit polyclonal antibody to RAE1 (RAE1 RNA export 1 homolog (S. pombe))

Product Data

• Application: IF, WB
• Recommended Dilution: ICC/IF:1:100-1:1000; WB:1:500-1:3000
• Reactivity: Bovine, Human (Predicted: Mouse, Pig, Rat, X. tropicalis), Xenopus, Zebrafish
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region within amino acids 307 and 368 of RAE1 (Uniprot ID#P78406)
• Buffer: 1XPBS, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 41 kDa
• Gene Name: ribonucleic acid export 1
• Database Link:
  NP_001015885
  P78406
• Background: Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
• Synonyms: dJ481F12.3; dJ800J21.1; MIG14; Mnrp41; MRNP41
• Note: Seq homology of immunogen across species: Mouse (100%), Rat (100%), Zebrafish (100%), Xenopus laevis (100%), Xenopus Tropicalis (100%), Pig (100%), Bovine (100%)

Reference Data