VPS16 Rabbit Polyclonal Antibody

CAT#: TA307915

Rabbit polyclonal antibody to VPS16 (vacuolar protein sorting 16 homolog (S. cerevisiae))

Product Images

Sample (30 ug of whole cell lysate). A: Molt-4. 7.5% SDS PAGE. TA307915 diluted at 1:1000.

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  Immunohistochemical analysis of paraffin-embedded SCC15 xenograft, using VPS16 (TA307915) antibody at 1:100 dilution.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human (Predicted: Bovine, Rhesus Monkey)
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide corresponding to a region within amino acids 715 and 804 of VPS16
• Formulation: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 95 kDa
• Gene Name: VPS16, CORVET/HOPS core subunit
• Database Link:
  NP_072097
  Entrez Gene 64601 Human
  UniProt ID Q9H269
• Background: Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps16 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. [provided by RefSeq]
• Synonyms: hVPS16
• Note: Seq homology of immunogen across species: Rhesus Monkey (100%), Bovine (100%)

Reference Data

• Protein Families: Druggable Genome