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TIM 1 (HAVCR1) Rabbit Polyclonal Antibody

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SKU
TA306320
Rabbit Polyclonal TIM-1 Antibody
Size:
100 ug
Conjugation:
Unconjugated
  $640.00
2 Weeks*
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Specifications
Specifications
Product Data
Application IF, IHC, WB
Recommended Dilution WB: 1 - 2 ug/mL, ICC: 10 ug/mL, IF: 20 ug/mL
Reactivity Human, Mouse
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen TIM-1 antibody was raised against a 16 amino acid peptide from near the amino terminus of human TIM-1.
Buffer PBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column
Conjugation Unconjugated
Storage Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name hepatitis A virus cellular receptor 1
Database Link
Background The human form of TIM-1 was initially discovered as a membrane glycoprotein through which the hepatitis A virus can gain entry into a cell. It was also identified as kidney injury molecule 1 (Kim-1), a predicted adhesion molecule that is upregulated on the surfaces of kidney epithelia. It is also expressed on T helper 2 (Th2) cells of the immune system, and following the binding of its natural ligand TIM-4, stimulates T cell expansion and cytokine production in response to viral challenge. It has been suggested that hyperactivation of TIM-1 leads to an increased level of Th2 responsiveness and asthma susceptibility, and antibodies to TIM-1 may therefore be a novel approach to treating asthma.
Synonyms HAVCR; HAVCR-1; KIM-1; KIM1; TIM; TIM-1; TIM1; TIMD-1; TIMD1
Reference Data
Protein Categories CD Markers, Membrane Proteins
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Documents
Resources

file-alt Citations

miR29b regulates aberrant methylation in In-Vitro diabetic nephropathy model of renal proximal tubular cells
Gondaliya, Dasare, Srivastava et al
PLoS ONE (2018) 13 (11), e0208044 DOI: 10.1371/journal.pone.0208044
AI Summary: In this study, the OriGene KIM-1 antibody was used to detect levels of the kidney injury biomarker KIM-1 by Western blot, helping to assess kidney damage in the in vitro diabetic nephropathy model.
Snippet: e by using RTA Trans Turbo kit (BioRad). Detection of specific proteins were done by using primary antibody against (DNMT3A 1:2000, Abcam), (DNMT3B 1:250, Sigma), (DNMT1 1:1000, abcam), (KIM-1 1:500, origene), (fibronectin, 1:250 Abcam) and (β-actin 1:5000, Santacruz) at 4˚C overnight. After incubation of primary antibody, membrane was washed with 0.1% TBST and then membrane was incubated with s;R...
FigureFigureFigure
WB
Showing 1-1 of 1 papers.
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