IL23 (IL23A) Rabbit Polyclonal Antibody

SKU
TA306315
Rabbit Polyclonal IL-23 Antibody
  $640.00
5 Days*
Bulk/Customize
Specifications
Specifications
Product Data
Application IF, IHC, WB
Recommended Dilution WB: 1 - 2 ug/mL, ICC: 2 ug/mL, IF: 20 ug/mL
Reactivity Human, Mouse
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen IL-23 antibody was raised against a 16 amino acid peptide from near the amino terminus of human IL-23.
Buffer PBS containing 0.02% sodium azide.
Concentration 1ug/ul
Purification Affinity chromatography purified via peptide column
Conjugation Unconjugated
Storage Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name interleukin 23 subunit alpha
Database Link
Background Like interleukin-27 (IL-27), IL-23 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the IL-12p40 subunit and a novel p19 subunit. IL-23 is secreted by activated dendritic cells, macrophages, and monocytes (3,4). Its biological activities include enhancing the proliferation of memory T cells and the production of IFN-gamma, IL-12, and TNF-alpha from activated T cells, and can stimulate macrophages to produce TNF-alpha and nitric oxide. It has also been shown to possess potent anti-tumor and anti-metastatic activity in mouse models of cancer, suggesting a potential role for IL-23 in therapeutic treatment of cancer.
Synonyms IL-23; IL-23A; IL23P19; P19; SGRF
Reference Data
Protein Categories Cytokines, Secreated Proteins
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