SARM(SARM1) Rabbit Polyclonal Antibody

CAT#: TA306162

Rabbit Polyclonal SARM Antibody

Antibody Service


 Product Datasheet for 'TA306162'

USD 371


Availability*
2 Weeks

Size
    • 100 ug

Product images

Specifications

Product Data
Applications WB, IF
Recommend Dilution WB: 0.5 - 2 ug/mL, ICC: 2 ug/mL, IF: 2 ug/mL
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen SARM antibody was raised against a peptide corresponding to amino acids near the C-terminus of human SARM.
Isotype IgG
Formulation PBS containing 0.02% sodium azide.
Concentration 1mg/ml
Purification Ion exchange chromatography purified
Gene Name sterile alpha and TIR motif containing 1
Background Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. SARM (SAM and ARM-containing protein), along with other molecules such as TIRP, TRIF, TIRAP, and MyD88, is thought to serve as an adaptor protein for the TLRs that allows for the activation of downstream kinases and NF-kappaB, and ultimately the expression of proteins involved in host defense. While SARM has not been conclusively shown to associate directly with TLRs, the presence of a Toll-interluekin-1 (TIR) domain in SARM is consistent with a role as a signaling molecule.
Synonyms MyD88-5|SAMD2|SARM
Reference Data
Protein Families Druggable Genome
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations