TACI (TNFRSF13B) Rabbit Polyclonal Antibody
Specifications
| Product Data | |
| Application | IF, WB |
|---|---|
| Recommended Dilution | WB: 5 ug/mL, ICC: 2 ug/mL |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | TACI antibody was raised against a synthetic peptide mapping at the amino terminus of human TACI . |
| Buffer | PBS containing 0.02% sodium azide. |
| Concentration | 1ug/ul |
| Purification | Affinity chromatography purified via peptide column |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | tumor necrosis factor receptor superfamily member 13B |
| Database Link | |
| Background | Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL-1/THANK/zTNF4 (1-4) and April/TALL-2, respectively, (3,5). BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion (1,2). April regulates immunological and non-immunological cell growth. Three receptors, BCMA, TACI, and BAFF-R, for BAFF and April were recently identified (6,7). TACI, like BCMA, binds BAFF and April. TACI and its ligands regulate humoral immune responses, activate NF-kappaB and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases. |
| Synonyms | CD267; CVID; CVID2; IGAD2; RYZN; TACI; TNFRSF14B |
| Reference Data | |
| Protein Categories | CD Markers, Immune system diseases, Intracellular Proteins, Membrane Proteins |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Cytokine-cytokine receptor interaction, Primary immunodeficiency |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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