GRIK3 Goat Polyclonal Antibody
Specifications
| Product Data | |
| Application | WB |
|---|---|
| Recommended Dilution | WB: 0.05-0.2ug/ml. |
| Reactivity | Cow), Dog, Mouse (Expected from sequence similarity: Human, Rat |
| Antibody Host | Goat |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Peptide with sequence C-KIRQLPIDSDDSRP, from the internal region of the protein sequence according to NP_000822.2. |
| Buffer | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Concentration | lot specific |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Gene Name | glutamate ionotropic receptor kainate type subunit 3 |
| Database Link | |
| Background | Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics. provided by RefSeq |
| Synonyms | EAA5; GLR7; GluK3; GLUR7; GluR7a |
| Reference Data | |
| Protein Categories | Membrane Proteins |
| Protein Families | Druggable Genome, Ion Channels: Glutamate Receptors, Transmembrane |
| Protein Pathways | Neuroactive ligand-receptor interaction |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Citations
S-allyl L-cysteine protects the retina against kainate excitotoxicity in the rat
Chao, Chen, Liu
Am. J. Chin. Med. (2014) 42 (3), 693-708 DOI: 10.1142/S0192415X14500451
Chao, Chen, Liu
Am. J. Chin. Med. (2014) 42 (3), 693-708 DOI: 10.1142/S0192415X14500451
AI Summary: In this study, the OriGene goat anti-GluR7 antibody was used to detect GluR7 kainate receptors in retinal tissues, contributing to the investigation of S-allyl L-cysteine’s protective effects against kainate-induced retinal excitotoxicity in rats.
Snippet: C with various primary antibodies, namely, rabbit polyclonal anti-KA2 antibody (1:2500;Abcam Inc., MA, USA), goat anti- GluR7 antibody (1:1000;Origene Technologies, INC, Rockville, MD, USA), and mouse monoclonal [AC-15] anti-β-actin antibody (1:5000;Abcam ... Cite SaveSaving
Showing 1-1 of 1 papers.
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