CHRNB1 Goat Polyclonal Antibody

CAT#: TA305851

Goat Anti-CHRNB1 / ACHRB Antibody

Product Images

TA305851 (1ug/ml) staining of human cerebellum lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1-3ug/ml.
• Reactivities: Human (Expected from sequence similarity: Mouse, Rat, Cow)
• Host: Goat
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Peptide with sequence C-QEQEDHDALKED, from the internal region of the protein sequence according to NP_000738.2.
• Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
• Concentration: lot specific
• Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: cholinergic receptor nicotinic beta 1 subunit
• Database Link:
  NP_000738
  Entrez Gene 11443 MouseEntrez Gene 24261 RatEntrez Gene 1140 Human
  UniProt ID P11230
• Background: The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome. [provided by RefSeq]
• Synonyms: ACHRB; CHRNB; CMS1D; CMS2A; CMS2C; SCCMS

Reference Data

• Protein Families: Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane