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ALS2 Goat Polyclonal Antibody

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SKU
TA305806
Goat Anti-Alsin / ALS2 Antibody
Size:
100 ug
Conjugation:
Unconjugated
  $565.00
5 Days*
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Specifications
Specifications
Product Data
Application IHC
Recommended Dilution IHC: 3-5ug/ml.
Reactivity Cow), Dog, Human (Expected from sequence similarity: Mouse, Rat
Antibody Host Goat
Isotype IgG
Clonality Polyclonal
Immunogen Peptide with sequence LKACYYQIQREKLN, from the C Terminus of the protein sequence according to NP_065970.2.
Buffer 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Concentration lot specific
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name ALS2, alsin Rho guanine nucleotide exchange factor
Database Link
Background The protein encoded by this gene contains an ATS1/RCC1-like domain, a RhoGEF domain, and a vacuolar protein sorting 9 (VPS9) domain, all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments, and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene. provided by RefSeq
Synonyms ALS2CR6; ALSJ; IAHSP; PLSJ
Reference Data
Protein Categories Growth Factors, Intracellular Proteins, Nervous system: Neurodegenerative diseases
Protein Families Druggable Genome
Protein Pathways Amyotrophic lateral sclerosis (ALS)
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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