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Caveolin 3 (CAV3) Goat Polyclonal Antibody

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SKU
TA305791
Goat Anti-CAV3 Antibody
Size:
100 ug
Conjugation:
Unconjugated
  $565.00
In Stock*
Bulk/Customize

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View other "Caveolin 3 or NM_001234" antibodies

Specifications
Specifications
Product Data
Application IHC, WB
Recommended Dilution WB: 0.1-0.3 µg/ml. IHC: 3-5 µg/ml.
Reactivity Cow), Human, Mouse, Pig (Expected from sequence similarity: Dog, Rat
Antibody Host Goat
Isotype IgG
Clonality Polyclonal
Immunogen Peptide with sequence EHTDLEAQIVKDIH-C, from the N Terminus of the protein sequence according to NP_203123.1.
Buffer 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Concentration lot specific
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name caveolin 3
Database Link
Background This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites. provided by RefSeq
Synonyms LGMD1C; LQT9; VIP-21; VIP21
Reference Data
Protein Categories Cardiovascular diseases, Growth Factors, Membrane Proteins
Protein Families Druggable Genome, Transmembrane
Protein Pathways Focal adhesion
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Documents
Resources

file-alt Citations

Genetic Defect in Submucosal Gland-Associated Caveolin-3: A New Paradigm in Esophageal Adenocarcinoma Risk
Garman, Purkayastha, Hogue et al
Gastroenterology (2023)
Cited by 6
AI Summary: OriGene's CAV3 antibody (TA305791) was used in this study to detect Caveolin-3 protein expression, contributing to the investigation of its genetic defects in esophageal adenocarcinoma risk.
Snippet: Vendor sources and antibody dilutions are CAV3 (Origene TA305791, 1:100) and smooth muscle actin (Agilent M0851 (Santa Clara, CA, 1:100);dilutions were performed Save;Vendor sources and antibody dilutions are CAV3 (Origene TA305791, 1:100) and smooth muscle actin (Agilent M0851 (Santa Clara, CA, 1:100);dilutions were performed in CAS-Block and incubations for CAV3 was overnight at 4C followed by secondary antibody donkey anti-goat (Thermo Fisher, AF555 A21432) diluted 1:1000 in 1%
Showing 1-1 of 1 papers.
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