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NANOG Goat Polyclonal Antibody

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SKU
TA303206
Goat Polyclonal Antibody against NANOG (C-terminal)
Size:
100 ug
Conjugation:
Unconjugated
  $565.00
5 Days*
Bulk/Customize

Frequently Bought Together (2)

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View other "NANOG or NM_024865" antibodies

Specifications
Specifications
Product Data
Application WB
Recommended Dilution ELISA: 1:128,000. WB: 0.05-0.1µg/ml.
Reactivity Human
Antibody Host Goat
Isotype IgG
Clonality Polyclonal
Immunogen Peptide with sequence C-DLFLNYSMNMQPED, from the C Terminus of the protein sequence according to NP_079141.1.
Buffer Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration lot specific
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name Nanog homeobox
Database Link
Background Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes (By similarity). Acts as a transcriptional activator or repressor (By similarity). Binds optimally to the DNA consensus sequence 5'-CGGACGCGCATTANGC-3' (By similarity). When overexpressed, promotes cells to enter into S phase and proliferation (By similarity)
Synonyms homeobox transcription factor Nanog; homeobox transcription factor Nanog-delta 48; Nanog homeobox
Reference Data
Protein Categories Intracellular Proteins, Transciption Factors
Protein Families Cancer stem cells, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Stem cell - Pluripotency
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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