CARD15 (NOD2) Goat Polyclonal Antibody

SKU
TA303142
Goat Polyclonal Antibody against CARD15
  $565.00
5 Days*
Bulk/Customize
Specifications
Specifications
Product Data
Application WB
Recommended Dilution ELISA: 1:64,000. WB: 0.1-0.3µg/ml.
Reactivity Human (Expected from sequence similarity: Mouse, Rat)
Antibody Host Goat
Isotype IgG
Clonality Polyclonal
Immunogen Peptide with sequence KFRFTDRERHCSPTD, from the internal region of the protein sequence according to NP_071445.1.
Buffer Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration lot specific
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name nucleotide binding oligomerization domain containing 2
Database Link
Background This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. provided by RefSeq
Synonyms ACUG; BLAU; CARD15; CD; CLR16.3; IBD1; NLRC2; NOD2B; PSORAS1
Reference Data
Protein Categories Allergies and autoimmune diseases, Cytokines, Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways NOD-like receptor signaling pathway
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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