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VAV3 Goat Polyclonal Antibody

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SKU
TA302958
Goat Polyclonal Antibody against VAV3
Size:
100 ug
Conjugation:
Unconjugated
  $565.00
5 Days*
Bulk/Customize

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View other "VAV3 or NM_001079874" antibodies

Specifications
Specifications
Product Data
Application WB
Recommended Dilution ELISA: 1:1:32000. WB:0.5-1.5µg/ml.
Reactivity Human (Expected from sequence similarity: Dog)
Antibody Host Goat
Isotype IgG
Clonality Polyclonal
Immunogen Peptide with sequence CSGEQGTLKLPEK, from the internal region of the protein sequence according to NP_006104.4; NP_001073343.1.
Buffer Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration lot specific
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name vav guanine nucleotide exchange factor 3
Database Link
Background This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. provided by RefSeq
Synonyms FLJ40431
Reference Data
Protein Categories Growth Factors, Intracellular Proteins
Protein Families Druggable Genome
Protein Pathways B cell receptor signaling pathway, Chemokine signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, Leukocyte transendothelial migration, Natural killer cell mediated cytotoxicity, Regulation of actin cytoskeleton, T cell receptor signaling pathway
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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