BAG2 Goat Polyclonal Antibody

SKU TA302728

Goat Polyclonal Antibody against BAG2

Product Data

• Application: WB
• Recommended Dilution: ELISA: 1:8,000. WB: 0.1-0.3µg/ml.
• Reactivity: Cow), Human (Expected from sequence similarity: Pig
• Antibody Host: Goat
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Peptide with sequence CSKTLQQNAESRFN, from the C Terminus of the protein sequence according to NP_004273.1.
• Buffer: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Concentration: lot specific
• Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: BCL2 associated athanogene 2
• Database Link:
  NP_004273
  O95816
• Background: BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.
• Synonyms: BAG-2; dJ417I1.2

Reference Data

• Protein Families: Druggable Genome