NCF1 Goat Polyclonal Antibody

SKU TA302677

Goat Polyclonal Antibody against NCF1 / p47phox

Product Data

• Application: IHC, WB
• Recommended Dilution: ELISA:1:20000. WB:0.5-1.5µg/ml.IHC:5µg/ml
• Reactivity: Cow), Human (Expected from sequence similarity: Mouse, Pig, Rabbit, Rat
• Antibody Host: Goat
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Peptide with sequence C-SESTKRKLASAV, from the C Terminus of the protein sequence according to NP_000256.3.
• Buffer: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 44.5 kDa
• Gene Name: neutrophil cytosolic factor 1
• Database Link:
  NP_000256
  P14598
• Background: The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease. [provided by RefSeq]
• Synonyms: NCF1A; NOXO2; p47phox; SH3PXD1A

Reference Data

• Protein Pathways: Chemokine signaling pathway, Fc gamma R-mediated phagocytosis, Leukocyte transendothelial migration, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton