NCF1 Goat Polyclonal Antibody
Specifications
| Product Data | |
| Application | IHC, WB |
|---|---|
| Recommended Dilution | ELISA:1:20000. WB:0.5-1.5µg/ml.IHC:5µg/ml |
| Reactivity | Cow), Human (Expected from sequence similarity: Mouse, Pig, Rabbit, Rat |
| Antibody Host | Goat |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Peptide with sequence C-SESTKRKLASAV, from the C Terminus of the protein sequence according to NP_000256.3. |
| Buffer | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 44.5 kDa |
| Gene Name | neutrophil cytosolic factor 1 |
| Database Link | |
| Background | The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease. provided by RefSeq |
| Synonyms | NCF1A; NOXO2; p47phox; SH3PXD1A |
| Reference Data | |
| Protein Categories | Growth Factors, Immune system diseases, Intracellular Proteins |
| Protein Pathways | Chemokine signaling pathway, Fc gamma R-mediated phagocytosis, Leukocyte transendothelial migration, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton |
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