Bak (BAK1) Goat Polyclonal Antibody

SKU
TA302647
Goat Polyclonal Antibody against BAK1
  $565.00
In Stock*
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Specifications
Specifications
Product Data
Application WB
Recommended Dilution WB: 0.5-1µg/ml.
Reactivity Human (Expected from sequence similarity: Mouse, Pig), Rat
Antibody Host Goat
Isotype IgG
Clonality Polyclonal
Immunogen Peptide with sequence ASGQGPGPPRQE-C, from the N Terminus of the protein sequence according to NP_001179.
Buffer Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 23.2 kDa
Gene Name BCL2 antagonist/killer 1
Database Link
Background The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. provided by RefSeq
Synonyms BAK; BAK-LIKE; BCL2L7; CDN1
Reference Data
Protein Categories Membrane Proteins
Protein Families Druggable Genome, Stem cell - Pluripotency, Transmembrane
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Documents
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file-alt Citations

MicroRNA-29c Correlates with Neuroprotection Induced by FNS by Targeting Both Birc2 and Bak1 in Rat Brain after Stroke
Huang, Li, Pang et al
CNS Neurosci Ther (2015)
Cited by 43
AI Summary: In this study, the OriGene Bak1 antibody (TA302647) was used to detect Bak1 protein levels by Western blot, helping to assess how microRNA-29c regulates Bak1 expression in the neuroprotective effects of fastigial nucleus stimulation after stroke.
Snippet: Abcam, Cambridge, UK) and GAPDH (1:5000;AG019, Beyotime), and then washed and incubated with secondary 1:10,000 anti-rabbit antibody (042-06-18-06;KPL, Washington, USA) at room temperature for 2 h. There also are Bak1 (1:500, TA302647;Origene, MD ... Cite SaveSaving
WB
Showing 1-1 of 1 papers.
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