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P4HA1 Goat Polyclonal Antibody

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SKU
TA302527
Goat Polyclonal Antibody against P4HA1
Size:
100 ug
Conjugation:
Unconjugated
  $565.00
2 Weeks*
Bulk/Customize

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View other "P4HA1 or NM_000917" antibodies

Specifications
Specifications
Product Data
Application WB
Recommended Dilution ELISA: 1:32,000. WB: 0.1-0.1µg/ml.
Reactivity Dog), Human (Expected from sequence similarity: Mouse, Rat
Antibody Host Goat
Isotype IgG
Clonality Polyclonal
Immunogen Peptide with sequence C-DFARKDEPDAFKE, from the internal region of the protein sequence according to NP_000908.2; NP_001017962.1.
Buffer Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration lot specific
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 64596 Da
Gene Name prolyl 4-hydroxylase subunit alpha 1
Database Link
Background This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described. provided by RefSeq
Synonyms P4HA
Reference Data
Protein Categories Intracellular Proteins
Protein Families Druggable Genome, P450
Protein Pathways Arginine and proline metabolism, Metabolic pathways
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Documents
Resources

file-alt Citations

Type I Collagen Suspension Induces Neocollagenesis and Myodifferentiation in Fibroblasts In Vitro
Lombardi, Palumbo, Augello et al
Biomed Res Int (2020) 2020, 6093974 DOI: 10.1155/2020/6093974
Cited by 10
AI Summary: OriGene products contributed to this study by providing specific antibodies—namely, the anti-COL1A1 (TA806232), anti-COL3A1 (TA809167), and anti-HSP47 (TA500053) antibodies—which were used in western blot and immunofluorescence analyses to assess protein expression changes in fibroblasts treated with type I collagen suspension.
FigureFigureFigure
Showing 1-1 of 1 papers.
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