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GNRHR Goat Polyclonal Antibody

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SKU
TA302503
Goat Polyclonal Antibody against GRHR / LRHR
Size:
100 ug
Conjugation:
Unconjugated
  $565.00
5 Days*
Bulk/Customize

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View other "GNRHR or NM_000406" antibodies

Specifications
Specifications
Product Data
Application WB
Recommended Dilution ELISA: 1:32,000. WB: 0.5-1.5µg/ml.
Reactivity Human (Expected from sequence similarity: Dog)
Antibody Host Goat
Isotype IgG
Clonality Polyclonal
Immunogen Peptide with sequence C-QKWTQKKEKGK, from the internal region of the protein sequence according to NP_000397.1; NP_001012781.1.
Buffer Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration lot specific
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 41356 Da
Gene Name gonadotropin releasing hormone receptor
Database Link
Background This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene. provided by RefSeq
Synonyms GNRHR1; GRHR; HH7; LHRHR; LRHR
Reference Data
Protein Categories Endocrine and metabolic diseases, GPCR, Membrane Proteins
Protein Families Druggable Genome, GPCR, Transmembrane
Protein Pathways GnRH signaling pathway, Neuroactive ligand-receptor interaction
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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