DLC1 Goat Polyclonal Antibody

SKU
TA302467
Goat Polyclonal Antibody against DLC1 (Isoforms 1 and 3)
  $565.00
2 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Application IHC
Recommended Dilution ELISA: 1:32,000. WB: 5µg/ml.
Reactivity Human (Expected from sequence similarity: Mouse, Pig)
Antibody Host Goat
Isotype IgG
Clonality Polyclonal
Immunogen Peptide with sequence SVAIRKRSWEEHC, from the N Terminus of the protein sequence according to NP_872584.1; NP_079043.2.
Buffer Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 126464 Da
Gene Name DLC1 Rho GTPase activating protein
Database Link
Background This gene is deleted in the primary tumor of hepatocellular carcinoma. It maps to 8p22-p21.3, a region frequently deleted in solid tumors. It is suggested that this gene is a candidate tumor suppressor gene for human liver cancer, as well as for prostate, lung, colorectal, and breast cancers. Alternative splicing at this locus results in several transcript variants encoding different isoforms. provided by RefSeq
Synonyms ARHGAP7; HP; p122-RhoGAP; STARD12
Reference Data
Protein Categories Intracellular Proteins
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Documents
Resources

file-alt Citations

Identification of DLC-1 expression and methylation status in patients with non-small-cell lung cancer
Feng, Zhang, Wang et al
Mol Clin Oncol (2016) 4 (2), 249-254 DOI: 10.3892/mco.2015.681
Cited by 9
AI Summary: OriGene products, specifically the human DLC-1 cDNA clone and anti-DLC-1 antibody, were used in this study to measure DLC-1 gene expression and protein levels in lung tissue samples, enabling the researchers to demonstrate the downregulation and promoter methylation of DLC-1 in non-small-cell lung cancer.
Identification of DLC‑1 expression and methylation status in patients with non‑small‑cell lung cancer
Feng, Zhang, Wang et al
MOLECULAR AND CLINICAL ONCOLOGY (2016) 4, 249-254
AI Summary: OriGene’s goat polyclonal anti-DLC-1 antibody (cat. no. TA302467) was used in western blot analyses to detect DLC-1 protein expression in the study.
Snippet: …The primary antibody was goat polyclonal anti‑DLC‑1 antibody (dilution 1:800;cat. no. TA302467;OriGene, Rockville, MD, USA)
WB
Showing 1-2 of 2 papers.
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