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DKK4 Goat Polyclonal Antibody

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SKU
TA302466
Goat Polyclonal Antibody against DKK4
Size:
100 ug
Conjugation:
Unconjugated
  $565.00
In Stock*
Bulk/Customize

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View other "DKK4 or NM_014420" antibodies

Specifications
Specifications
Product Data
Application WB
Recommended Dilution WB: 1-3µg/ml.
Reactivity Dog, Human (Expected from sequence similarity: Mouse, Pig), Rat
Antibody Host Goat
Isotype IgG
Clonality Polyclonal
Immunogen Peptide with sequence RQHARLRVCQKIEKL, from the C Terminus of the protein sequence according to NP_055235.
Buffer Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 28499 Da
Gene Name dickkopf WNT signaling pathway inhibitor 4
Database Link
Background This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. Activity of this protein is modulated by binding to the Wnt co-receptor and the co-factor kremen 2. provided by RefSeq. COMPLETENESS: complete on the 3' end.
Synonyms DKK-4
Reference Data
Protein Categories Secreated Proteins
Protein Families Adult stem cells, Cancer stem cells, Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Stem cell relevant signaling - Wnt Signaling pathway
Protein Pathways Wnt signaling pathway
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Documents
Resources

file-alt Citations

DICKKOPF-4 activates the noncanonical c-Jun-NH2 kinase signaling pathway while inhibiting the Wnt-canonical pathway in human renal cell carcinoma
Hirata, Hinoda, Majid et al
Cancer (2011) 117 (8), 1649-60 DOI: 10.1002/cncr.25666
Cited by 39
AI Summary: OriGene contributed to this study by providing the full-length DKK4 cDNA clone (catalog number RC221217), which was used to generate DKK4-transfected cell lines for functional analysis of DKK4 in renal cell carcinoma.
Snippet: and protein expression of major TCF/β-catenin down-stream effectors (c-Myc and cyclinD1) was down-regulated in ... length combinational DNA fragment of DKK4 (GenBank accession number NM_014420, catalog number RC221217) were purchased from Origene (Rockville, Md
Showing 1-1 of 1 papers.
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