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BDKRB1 Goat Polyclonal Antibody

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SKU
TA302436
Goat Polyclonal Antibody against Bradykinin receptor B1
Size:
100 ug
Conjugation:
Unconjugated
  $565.00
In Stock*
Bulk/Customize

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View other "BDKRB1 or NM_000710" antibodies

Specifications
Specifications
Product Data
Application WB
Recommended Dilution ELISA: 1:1,000. WB: 2-4µg/ml.
Reactivity Human
Antibody Host Goat
Isotype IgG
Clonality Polyclonal
Immunogen Peptide with sequence KVWELYKQCTPK, from the internal region of the protein sequence according to NP_000701.2.
Buffer Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 44120 Da
Gene Name bradykinin receptor B1
Database Link
Background Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. provided by RefSeq
Synonyms B1BKR; B1R; BDKRB2; BKB1R; BKR1; BRADYB1
Reference Data
Protein Categories GPCR, Membrane Proteins
Protein Families Druggable Genome, GPCR, Transmembrane
Protein Pathways Calcium signaling pathway, Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Regulation of actin cytoskeleton
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Documents
Resources

file-alt Citations

Genetic variation and gender determine bradykinin type 1 receptor responses in human tissue: implications for the ACE inhibitor-induced effects in patients with coronary artery disease
Wu, Roks, Leijten et al
Clin. Sci. (2013)
AI Summary: OriGene's anti-B1 receptor antibody was used for Western blot analysis to detect B1 receptor protein levels in human tissue samples, helping to assess the impact of genetic variation on bradykinin B1 receptor expression.
Snippet: phosphatase inhibitor cocktail 3 (Sigma-Aldrich). Lysates were analyzed by standard Western blotting techniques under denaturating conditions, making use of an anti-B1 receptor antibody (Origene). In 16 samples (11 AA, 5
WB
Showing 1-1 of 1 papers.
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