TAOK3 Rabbit Polyclonal Antibody

CAT#: TA302258

Rabbit Polyclonal Antibody against TAOK3 (C-term)

Product Images

Western blot analysis of TAOK3 (arrow) using rabbit polyclonal TAOK3 Antibody (C-term) (Cat.#TA302258). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the TAOK3 gene (Lane 2) (Origene Technologies).

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  Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with TAOK3 antibody (C-term) (Cat.#TA302258), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1:1000, IHC: 1:10~50
• Reactivities: Human (Predicted: Mouse, Rat, Chicken, Xenopus)
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This JIK (TAOK3) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 671-700 amino acids from the C-terminal region of human JIK (TAOK3).
• Formulation: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
• Concentration: lot specific
• Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 105275 Da
• Gene Name: TAO kinase 3
• Database Link:
  NP_057365
  Entrez Gene 304530 RatEntrez Gene 330177 MouseEntrez Gene 51347 Human
  UniProt ID Q9H2K8
• Background: TAOK3 is negatively regulated by epidermal growth factor (EGF) and Inhibits the basal activity of Jun kinase. When TAOK3 is overexpressed, it may activate ERK1/ERK2 and JNK/SAPK.
• Synonyms: DPK; JIK; MAP3K18

Reference Data

• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: MAPK signaling pathway